n-acetyl cysteine inhibits endothelin-1-induced ros dependent cardiac hypertrophy through superoxide dismutase regulation
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N-Acetyl Cysteine Inhibits Endothelin-1-Induced ROS Dependent Cardiac Hypertrophy through Superoxide Dismutase Regulation
OBJECTIVE Oxidative stress down regulates antioxidant enzymes including superoxide dismutase (SOD) and contributes to the development of cardiac hypertrophy. N-Acetyl cysteine (NAC) can enhance the SOD activity, so the aim of this study is to highlight the inhibitory role of NAC against endothelin-1 (ET-1)-induced cardiac hypertrophy. MATERIALS AND METHODS In this experimental study at QAU fr...
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عنوان ژورنال:
cell journalجلد ۱۷، شماره ۲، صفحات ۳۵۵-۳۶۰
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